The Motivational Impact of Nicotine and its Role in Tobacco by Rick A. Bevins, Anthony R. Caggiula

By Rick A. Bevins, Anthony R. Caggiula

Tobacco kills extra humans around the world than any criminal or unlawful drug; the collective advantages of quitting smoking are considerable, from more advantageous future health, elevated existence expectancy, and less ill days to much less tension on households and wellbeing and fitness care prone. Tobacco use and dependancy rely on the advanced interaction of neurochemical, genetic, own, and social factors—and nicotine, because the vital psychoactive factor in tobacco smoke, stands on the heart of this equation.

The Motivational impression of Nicotine and Its function in Tobacco Use assembles papers from the 55th Nebraska Symposium on Motivation in a multidimensional research of nicotine at paintings. those papers current facts, theories, and findings priceless in figuring out not just the mechanisms at the back of tobacco dependence and resistance to quitting, but in addition the problems eager about smoking cessation, preliminary use prevention, and relapse prevention. the various key parts coated include:

  • Molecular and neurobiological views at the motivational results of nicotine.
  • The motivational parts of nicotine dependence and the import of studying history.
  • The function of nicotine in making environmental cues linked to smoking extra reinforcing.
  • The results of pharmaco- and immunotherapies at the skill of mental cues to steer smoking habit.
  • Sex transformations in nicotine reinforcement and their implications for treatment.
  • The significance of yearning within the upkeep of smoking habit and in its relapse after quitting.

Given the ongoing influence of smoking on public well-being, The Motivational influence of Nicotine and Its position in Tobacco Use will allure a large viewers. This state-of-the-art info is essential to the medical psychologist, researcher, and policymaker focused on constructing extra effective remedies, more suitable remedy items, higher supply structures, or new avenues for research.

About the Nebraska Symposium on Motivation
The Nebraska Symposium on Motivation has been subsidized via the dep. of Psychology on the collage of Nebraska-Lincoln for the reason that 1953. every year the Symposium invitations major students from world wide to talk at a convention dedicated to an issue of present curiosity to psychology, the court cases of that are released in an edited volume.

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Changeux, J. , & Chemouilli, P. (1984). Acetylcholine receptor: An allosteric protein. Science, 225(4668), 1335–1345. , & Soubrie, P. (2005). Nicotine-associated cues maintain nicotine-seeking behavior in rats several weeks after nicotine withdrawal: Reversal by the cannabinoid (CB1) receptor antagonist, rimonabant (SR141716). Neuropsychopharmacology, 30(1), 145–155. Corrigall, W. , Coen, K. , & Adamson, K. L. (1994). Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area.

Russell, M. A. (1989). Subjective and behavioural effects of nicotine in humans: Some sources of individual variation. Progress in Brain Research, 79, 289–302. , Murphy, K. , McIntosh, J. , Marks, M. , Collins, A. , et al. (2004). Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. Molecular Pharmacology, 65(6), 1526–1535. , Grady, S. , Collins, A. , McIntosh, J. , & Marks, M. J. (2005). The subunit composition and pharmacology of alpha-conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay.

Meinerz, N. , Reynolds, A. , Picciotto, M. , Changeux, J. , et al. (2001). Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: A function mediated by a different nachr than dopamine release from striatum. The Journal Neurochemistry, 76(1), 258–268. Greengard, P. (2001). The neurobiology of slow synaptic transmission. Science, 294(5544), 1024–1030. , & Svensson, T. H. (1986). Nicotinic effects on the firing pattern of midbrain dopamine neurons. Acta Physiologica Scandinavica, 128(3), 351–358.

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